Details for gene set NCI_IL1-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	set02_ATM_minus_versus_BT_ATM_minus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NCI_IL1-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.41298983
Normalized Enrichment Score (NES)	-1.8719213
Nominal p-value	0.0
FDR q-value	0.040406127
FWER p-Value	0.459

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL2RA	15	4.747	0.0152	No
2	NUP214	64	3.714	0.0254	No
3	RPS6KA5	107	3.380	0.0348	No
4	CREB1	126	3.257	0.0449	No
5	LCK	137	3.203	0.0551	No
6	MAP2K6	175	2.990	0.0634	No
7	ITCH	197	2.938	0.0723	No
8	CSNK2A1	381	2.459	0.0721	No
9	PRKCA	397	2.430	0.0795	No
10	CASP3	413	2.406	0.0869	No
11	ATF2	444	2.361	0.0934	No
12	MAP3K7	448	2.353	0.1011	No
13	CREBBP	519	2.250	0.1055	No
14	YWHAZ	622	2.135	0.1079	No
15	IL5	751	2.009	0.1087	No
16	GSK3B	765	1.997	0.1148	No
17	PIK3CA	824	1.937	0.1186	No
18	PLA2G4A	906	1.879	0.1212	No
19	HBP1	986	1.830	0.1237	No
20	TMED7	1099	1.758	0.1244	No
21	EIF4E	1119	1.747	0.1294	No
22	CTLA4	1130	1.742	0.1348	No
23	MAPK8	1169	1.724	0.1388	No
24	MAP3K7IP1	1279	1.667	0.1394	No
25	CAMK4	1351	1.628	0.1415	No
26	SYK	1418	1.598	0.1439	No
27	RAB5A	1531	1.549	0.1439	No
28	YWHAE	1550	1.540	0.1482	No
29	TRAF6	1621	1.510	0.1501	No
30	CSNK1A1	1654	1.498	0.1536	No
31	ESR1	1688	1.488	0.1571	No
32	PPARGC1A	1723	1.472	0.1604	No
33	MITF	2097	1.330	0.1477	No
34	PIK3R1	2157	1.312	0.1494	No
35	CDC25B	2332	1.248	0.1456	No
36	PTPRK	2458	1.209	0.1439	No
37	PRKCE	2610	1.173	0.1409	No
38	POU2F1	2833	1.121	0.1344	No
39	RAN	3501	0.968	0.1070	No
40	CEBPB	3658	0.937	0.1030	No
41	PIM1	3908	0.888	0.0945	No
42	ERC1	3923	0.885	0.0968	No
43	MEF2A	3968	0.878	0.0977	No
44	MALT1	4026	0.868	0.0980	No
45	PAK3	4071	0.860	0.0989	No
46	KPNB1	4321	0.818	0.0902	No
47	MAP3K7IP2	4322	0.818	0.0929	No
48	TH	4459	0.792	0.0893	No
49	BAD	4507	0.786	0.0898	No
50	UBE2D3	4979	0.711	0.0705	No
51	EP300	5873	0.578	0.0314	No
52	FASLG	5895	0.575	0.0324	No
53	NFATC3	5945	0.567	0.0320	No
54	RALA	5982	0.562	0.0322	No
55	IL4	5986	0.560	0.0340	No
56	CHUK	6349	0.506	0.0190	No
57	IRAK1	7424	0.365	-0.0291	No
58	E2F1	7467	0.357	-0.0298	No
59	XPO1	7628	0.335	-0.0361	No
60	CDK4	7918	0.298	-0.0484	No
61	FKBP8	8018	0.285	-0.0519	No
62	PPARG	8381	0.235	-0.0678	No
63	FGR	8504	0.217	-0.0727	No
64	MAP3K1	8906	0.161	-0.0906	No
65	ATF1	9205	0.120	-0.1039	No
66	TNFRSF1A	9263	0.111	-0.1061	No
67	IL3	9524	0.071	-0.1178	No
68	CALM2	10266	-0.045	-0.1517	No
69	EGR4	10291	-0.048	-0.1527	No
70	CASP1	10532	-0.083	-0.1634	No
71	AKAP5	10935	-0.146	-0.1814	No
72	IL1A	10944	-0.147	-0.1813	No
73	RAF1	11386	-0.204	-0.2009	No
74	PAK2	12116	-0.285	-0.2334	No
75	DDIT3	12521	-0.335	-0.2509	No
76	TBX21	12958	-0.386	-0.2696	No
77	BLK	13045	-0.396	-0.2722	No
78	MAP3K8	13234	-0.417	-0.2795	No
79	PRKCI	13268	-0.420	-0.2796	No
80	MAP2K3	13472	-0.447	-0.2874	No
81	IL1R1	13480	-0.449	-0.2862	No
82	DUSP16	13526	-0.454	-0.2868	No
83	SRC	13765	-0.482	-0.2961	No
84	ELK4	13831	-0.491	-0.2974	No
85	USF1	13855	-0.493	-0.2969	No
86	CCM2	13964	-0.505	-0.3001	No
87	BIRC2	14071	-0.516	-0.3033	No
88	RNF128	14244	-0.538	-0.3094	No
89	CSF2	14405	-0.557	-0.3149	No
90	REL	14487	-0.568	-0.3167	No
91	YES1	14598	-0.581	-0.3198	No
92	MAP2K4	14640	-0.588	-0.3197	No
93	IL1B	14865	-0.614	-0.3280	No
94	HSPB1	15001	-0.628	-0.3321	No
95	YWHAQ	15062	-0.634	-0.3327	No
96	CALM1	15082	-0.637	-0.3314	No
97	IFNG	15303	-0.665	-0.3393	No
98	UBE2N	15327	-0.668	-0.3381	No
99	MAPK3	15401	-0.677	-0.3392	No
100	RIPK2	15580	-0.698	-0.3451	No
101	TSC2	15645	-0.708	-0.3456	No
102	EIF4EBP1	15826	-0.732	-0.3515	No
103	FOSL1	16325	-0.800	-0.3717	No
104	CD40LG	16375	-0.807	-0.3712	No
105	MAPKAPK2	16390	-0.809	-0.3692	No
106	NFKBIA	16391	-0.809	-0.3665	No
107	HCK	16436	-0.815	-0.3658	No
108	YWHAB	16464	-0.818	-0.3643	No
109	SLC9A1	16483	-0.821	-0.3623	No
110	PAK1	16504	-0.823	-0.3605	No
111	IRAK4	16616	-0.837	-0.3628	No
112	DUSP8	16645	-0.841	-0.3613	No
113	MAP3K14	16757	-0.855	-0.3635	No
114	RIPK1	16874	-0.871	-0.3659	No
115	PTGS2	17046	-0.900	-0.3708	No
116	GATA3	17055	-0.902	-0.3681	No
117	MYD88	17441	-0.960	-0.3826	No
118	MAPK9	17448	-0.962	-0.3797	No
119	ETV1	17507	-0.973	-0.3791	No
120	RELA	17566	-0.984	-0.3785	No
121	IL1R2	17621	-0.994	-0.3776	No
122	PRKACA	17631	-0.996	-0.3747	No
123	YWHAH	17687	-1.006	-0.3739	No
124	IL1RN	18058	-1.069	-0.3873	No
125	DGKA	18084	-1.073	-0.3848	No
126	JUN	18099	-1.076	-0.3819	No
127	RPS6KA4	18117	-1.078	-0.3791	No
128	MKNK1	18366	-1.127	-0.3867	No
129	BCL2	18625	-1.179	-0.3946	No
130	ATM	18685	-1.190	-0.3933	No
131	IKBKG	18928	-1.246	-0.4003	No
132	CYLD	18965	-1.255	-0.3977	No
133	PRKCQ	19298	-1.339	-0.4085	Yes
134	TNF	19341	-1.351	-0.4059	Yes
135	RAC1	19377	-1.360	-0.4030	Yes
136	CALM3	19591	-1.421	-0.4080	Yes
137	TP53	19687	-1.455	-0.4075	Yes
138	TNFAIP3	19726	-1.471	-0.4043	Yes
139	SQSTM1	19798	-1.497	-0.4026	Yes
140	FKBP1A	19825	-1.506	-0.3988	Yes
141	IRAK3	19914	-1.534	-0.3977	Yes
142	SFN	20083	-1.603	-0.4000	Yes
143	FYN	20107	-1.612	-0.3957	Yes
144	IKBKB	20132	-1.623	-0.3914	Yes
145	MEF2C	20238	-1.670	-0.3906	Yes
146	PRKCZ	20308	-1.703	-0.3881	Yes
147	SLC3A2	20423	-1.750	-0.3875	Yes
148	TOLLIP	20513	-1.805	-0.3855	Yes
149	PRKCD	20514	-1.805	-0.3795	Yes
150	SRF	20535	-1.816	-0.3743	Yes
151	MAF	20636	-1.867	-0.3727	Yes
152	PRKG1	20704	-1.910	-0.3694	Yes
153	DUSP10	20732	-1.927	-0.3642	Yes
154	LSP1	20764	-1.943	-0.3591	Yes
155	PTPN1	20769	-1.947	-0.3527	Yes
156	RALB	20823	-1.981	-0.3486	Yes
157	MAP3K12	20842	-1.995	-0.3427	Yes
158	MEF2D	20891	-2.028	-0.3381	Yes
159	GDI1	20903	-2.033	-0.3318	Yes
160	ATF6	20914	-2.044	-0.3255	Yes
161	NFKB1	20944	-2.065	-0.3199	Yes
162	MAPKAPK5	20969	-2.083	-0.3140	Yes
163	FBXW11	20996	-2.114	-0.3081	Yes
164	MAPK14	21120	-2.209	-0.3064	Yes
165	DUSP1	21121	-2.210	-0.2990	Yes
166	BCL10	21159	-2.247	-0.2932	Yes
167	ARRB2	21227	-2.318	-0.2885	Yes
168	FOXP3	21314	-2.435	-0.2843	Yes
169	MAPKAPK3	21325	-2.455	-0.2766	Yes
170	JUNB	21440	-2.670	-0.2729	Yes
171	CBLB	21453	-2.694	-0.2644	Yes
172	TCF3	21468	-2.726	-0.2559	Yes
173	MAP3K3	21546	-2.891	-0.2498	Yes
174	NFKB2	21615	-3.137	-0.2424	Yes
175	YWHAG	21678	-3.403	-0.2339	Yes
176	PRKCH	21736	-3.724	-0.2241	Yes
177	NFATC2	21737	-3.736	-0.2116	Yes
178	RELB	21749	-3.826	-0.1993	Yes
179	MAPK11	21793	-4.191	-0.1872	Yes
180	IRF4	21795	-4.216	-0.1732	Yes
181	BCL3	21865	-4.977	-0.1597	Yes
182	NFATC1	21871	-5.174	-0.1426	Yes
183	FOS	21917	-6.478	-0.1230	Yes
184	NR4A1	21923	-6.633	-0.1010	Yes
185	EGR1	21942	-8.847	-0.0723	Yes
186	EGR3	21943	-9.744	-0.0397	Yes
187	EGR2	21944	-11.902	0.0001	Yes